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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are often characterized as focusing on practical aspects of design, including recruitment and consent, adherence and the use routinely available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which used various investigators and had participants from different geographical regions. This type of heterogeneity which is vital for a pragmatic trial to be reliable and to reduce bias in the results, is also necessary. However too much heterogeneity could lead to problems with the design of the trial.

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Pragmatic trials seek to replicate real-life settings and achieve maximum external validity. They are typically ordered by policymakers and practitioners to guide their decisions. They can also be a great way to identify the causal relationship between an intervention and its results. However, they shouldn't be used to substitute for 프라그마틱 홈페이지 explanatory studies.

The concept of pragmatism is controversial and there are concerns about whether pragmatic trials should be used to replace explanation tests or if they are an alternative to them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove the clinical or physiological hypothesis as well as pragmatic trials, which guide the policy and practice of. They also suggested a framework for pragmatic trials, dubbed PRECIS.2 This tool sought to define the features of a practical trial which includes recruitment, design and delivery of the intervention, as well as monitoring.

The number of pragmatic trials is increasing. A recent Medline query using the keywords naturalistic and pragmatic, restricted to randomised controlled trials (RCTs), 프라그마틱 슬롯체험 returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to remember that the majority of these trials were conducted in primary care settings.